Abstract:The cemented filling body was prepared by using the full tailings of a lead-zinc mine as the filling aggregate and cement as the gelling agent. The physical and chemical properties of the full tailings were tested, and the three-factor four-level orthogonal test was designed to carry out a uniaxial compressive strength test. In addition, the sensitivity of the compressive strength of the full tailings cemented filling body to the lime-sand ratio, mass concentration and curing time was also studied, and the optimal ratio of filling slurry was recommended by multiple linear regression analysis of various factors. The results exhibit that when the non-uniformity coefficient of the whole tailings is larger than 5, it can be used as filling aggregate and the filling body made is dense; Besides, the compressive strength of cemented filling body is proportional to the lime-sand ratio, mass concentration and curing time. Furthermore, the sensitivity of limesand ratio, curing time and mass concentration to the compressive strength of the filling body from high to low is: lime-sand ratio> curing time> mass concentration. It is recommended that the optimal filling ratio of the mine is a lime-sand ratio of 1∶4, a mass concentration of 76%, and a curing time of 28d.