Abstract:The main sulfide minerals in a gold-silver-bearing copper-sulfur ore in Liaoning province are pyrite and chalcopyrite, which are uneven in particle size and closely coexist, and gold and silver are mainly fine particles. The experimental process of copper-sulfur mixed flotation-regrinding of mixed concentrate-separation of copper and sulfur was adopted. In the first stage of grinding, the fineness -0.074 mm content accounted for 59.7%, and the regrinding fineness -0.074 mm content accounted for 96.9%, sodium carbonate as pH regulator, butyl xanthate as collector, lime as inhibitor and ethyl xanthate as collector were used in mixed flotation of copper and sulfur, under appropriate dosage, the grade of copper and the recovery of copper were 27.52% and 83.46%. The grade of copper and sulfur were 38.48% and 49.62% respectively, the recovery of copper and sulfur were 13.89% and 80.98% respectively, and the total recovery of sulfur was 94.87%. The recoveries of associated gold and silver in copper concentrate are 50.70% and 53.78% respectively. Separation and recovery of cop and sulfur and effective recovery of associated element of gold and silver were realized.