Abstract:The copper grade the low-grade copper-molybdenum ore in Shaanxi is 0.32% and the molybdenum grade is 0.048%.The copper and molybdenum minerals mainly exist in the form of sulfide ore. The properties are complex that there are many kinds of minerals in the ore, which are closely distributed and fine dissemination size. According to the properties of the ore, the technological process of bulk flotation and separation of copper and molybdenum was adopted in the experiment. With lime as regulator and reagent L03 as collector, the mixed concentrate of copper and molybdenum was obtained by the bulk flotation which flow-sheet is one roughing, three refining and two scavenging process. Then regrinding the mixed concentrate, use sodium sulfide as inhibitor of copper minerals, sodium silicate as slurry dispersant and inhibitor of silicate gangue minerals , kerosene as collector, can separate copper and molybdenum with the flow-sheet which one roughing, five refining and three scavenging. The copper concentrate with copper grade of 18.82% and copper recovery rate of 85.35% and molybdenum concentrate with molybdenum grade of 47.14% and molybdenum recovery rate of 79.24% were obtained by the final closed-circuit flotation test process, the indicator is nearly ideal.